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Topiramate, generally referred to as its brand name Topamax, is a medication prescribed to control seizures and prevent migraines from developing in individuals with these conditions. Although Topamax does not cure seizure or migraine disorders, it can be effective in substantially reducing symptoms when used in isolation or in combination with other medications. Topiramate belongs to a class of drugs known as anticonvulsants that work by altering excitation levels in the brain.

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The drug is approved for use in pediatric and adult populations as an anti-seizure medication. Caution should be exercised when taking Topamax as it can cause changes in mood such as panic attacks, aggression, depression, mania, or increase the risk of suicidal ideation and planning. Pregnant women and those breastfeeding should consult their physician prior to beginning or continuing with this medication as may be harmful to the fetus and pass through breast milk. The medication is usually taken twice daily, once in the morning and once in the evening. It is critical to precisely follow the instructions that accompany the medication in order to ensure that the correct dosage is taken. If improvement is not seen, the dosage may be gradually increased until effectiveness is demonstrated.

Given that topiramate does not cure seizures, it is important for patients to avoid activities that may be dangerous with a seizure condition. There are certain populations for whom use may be contraindicated and therefore individuals need to disclose a full medical history prior to beginning the drug. Common side effects of Topamax include difficulty with concentration, drowsiness, depression, uncontrollable movements, heartburn, and dry mouth. More serious complications require immediate evaluation such as, worsening of seizures, appetite loss, and fever. Those taking the medication can refer to the information included to view a complete list of possible side effects.

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